A pharmacophore for compounds active against Ebola
I was looking through Pubmed yesterday looking for repurposing efforts applied to Ebola and found the paper by Madrid et al. This described many hits, including chloroquine and amodiaquine. Then I was...
View ArticleIn response to the NIH director
I just found a post by Dr. Antony Fauci and Dr. Francis Collins on Ebola. So I have added my 2 cents – lets see if it gets accepted and a response from some moderator (..Tax dollars well spent – who...
View ArticleUnderwhelming big pharma response to Ebola – I urge more collaboration
A few weeks ago I asked where are the big pharma companies who have been largely surprisingly quiet during the Ebola epidemic. Today I see a press release announcing J&J will have their vaccine...
View ArticleCollaboration to find compounds active against Ebola
Our latest contribution to the Ebola literature came out today. A collaboration with Peter Madrid (SRI International), Robert Davey and Manu Anantpadma (Texas Biomedical Research Institute), Alex Clark...
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Select antimalarials saved lives of those infected with Ebola Virus
Lets start 2016 with a bang. Frequent Ebola collaborator Dr. Megan Coffee just pointed me to a new article in the New England Journal of Medicine that showed a ‘natural experiment’ of how fewer Ebola...
View ArticleAntimalarial being tested as possible Ebola virus drug -project started with...
Today we announced a new R21 grant from NCATS NIH awarded to Collaborations Pharmaceuticals, Inc andTexas Biomedical Research Institute. This continues the work published in F1000Research . What is...
View ArticleGetting to an in vivo active compound
Its been an incredibly fast paced year and hence my posting frequency has suffered. Perhaps its time to get back to writing . Today we had a press release with SRI so that triggered me to fill in the...
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